A rare cause of digital clubbing: pachydermoperiostosis
Zeineb Alaya, Walid Osman
The Pan African Medical Journal. ;25:194. doi:10.11604/pamj..25.194.10890

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Images in clinical medicine

A rare cause of digital clubbing: pachydermoperiostosis

Zeineb Alaya, Walid Osman
Pan Afr Med J. 2016; 25:194. doi:10.11604/pamj.2016.25.194.10890. Published 25 Nov 2016



A 35-year-old man of Tunisian origin complained of inflammatory arthralgia and he had noticed a progressive enlargement of his hands and feet as well as facial furrowing. On examination, he had thickening of the skin of the head and distal extremities and deep folds and furrows of the skin of the forehead (A), digital clubbing of fingers (B) and toes (C), spadelike enlargement of the hands and feet, hyperhidrosis of the hands and feet and seborrhea. Inflammation tests were disturbed. Radiographs showed periostosis of the long bones (D) and sacro-iliac osteosclerosis. After excluding secondary causes, primary hypertrophic osteoarthropathy also called pachydermoperiostosis (PDP) was established. This disease is characterised by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea; hyperhidrosis; periostosis of the long bones and digital clubbing. The treatment consisted in our case of analgesics and NSAIDs.


Corresponding author:
Zeineb Alaya, Department of Rheumatology, Farhat Hached Hospital, Faculty of Medicine of Sousse, Sousse, Tunisia
zeineb_a@hotmail.fr

©Zeineb Alaya et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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