Inflammatory linear verrucous epidermal nevus in a patient with diabetes

Yosra Htira, Faika Ben Mami

PAMJ. 2022; 41:139. Published 17 Feb 2022 | doi:10.11604/pamj.2022.41.139.33468

We present the case of a 43-year-old man with diabetes who had erythematous and eczematous oozing plaques over the right leg. There was no family history of similar complaints. The lesions appeared on the early childhood. He was initially treated with a topical corticosteroid–antibiotic combination and antihistamine for a diagnosis of atopic dermatitis. He had a partial response with reduction of oozing, erythema, and crusting, but the lesions persisted. Hair, trunk, nails, oral mucosae, and other organ systems were normal. Skin biopsy specimens from lesions over the leg showed psoriasiform hyperplasia of the epidermis with alternating areas of parakeratosis and hyperkeratosis, acanthosis, spongiosis, and upper dermal lymphocytic infiltrate. Based on the clinical and histologic features, the diagnosis of Inflammatory linear verrucous epidermal nevus (ILVEN) was made.
Corresponding author
Yosra Htira, Institut National de Nutrition et de Technologies Alimentaires, Tunis, Tunisia (

The Pan African Medical Journal (ISSN: 1937-8688) is a subsidiary of the Pan African Medical Journal. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.

Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, ESCI

Physical address: Kenya: 3rd Floor, Park Suite Building, Parkland Road, Nairobi. PoBox 38583-00100, tel: +254 (0)20-520-4356 | Cameroon: Immeuble TechnoPark Essos, Yaounde, PoBox: 10020 Yaounde, tel: +237 (0)24-309-5880