Congenital clitoromegaly in an adult

Mohammed Alae Touzani, Imad Ziouziou

PAMJ. 2019; 34:141. Published 12 Nov 2019 | doi:10.11604/pamj.2019.34.141.18149

Clitoromegaly is an abnormal enlargement of the clitoris. In adult, dimensional criteria are, according to Brodie, a minimum length hood and width of 27.4mm and 8mm. We here report the case of a 26 year female patient, with no previous personal history, who consults for primary amenorrhea with androgenization signs (hirsutism, deep voice…). Clinical examination showed a clitoromegaly and urogenital sinus persistency. The patient first underwent a karyotype that shows a female karyotype with no abnormalities (46,XX). Further explorations showed a 21-hydroxylase deficiency, with a congenital bilateral adrenal hyperplasia. Congenital adrenal hyperplasia (CAH) is defined by an increased size and metabolism of the adrenal glands due to enzymatic disorders, such as 21-hydroxylase deficiency. In women, this can lead to virilization of the external genitalia in 11% of patients, and a late diagnosis, such in this case, may result in the late discovery of androgenization signs, such as clitoromegaly. The treatment is clitoroplasty, which consist to reduce the clitoris size and preserve its sensitivity, with a vaginoplasty if there is an association with urogenital sinus persistency, if the patient is asking for it.
Corresponding author
Mohammed Alae Touzani, Department of Urology « B », Avicenne Hospital, Rabat, Morocco (

This image

Articles published in PAMJ are Open Access and distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0).

eISSN: 1937-8688

The Pan African Medical Journal (ISSN: 1937-8688) is a subsidiary of the Pan African Medical Journal. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.

Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, ESCI

Physical address: Kenya: 3rd Floor, Park Suite Building, Parkland Road, Nairobi. PoBox 38583-00100, tel: +254 (0)20-520-4356 | Cameroon: Immeuble TechnoPark Essos, Yaounde, PoBox: 10020 Yaounde, tel: +237 (0)24-309-5880