eISSN: 1937-8688

Extensive cutaneous involvement in pemphigus vulgaris in a pediatric patient: a rare clinical image

Sahil Vihirkar, Darshana Kumari Wankhede

PAMJ. 2026; 53:19. Published 16 Jan 2026 | DOI: 10.11604/pamj.2026.53.19.49727

Extensive cutaneous involvement in pemphigus vulgaris in a pediatric patient: a rare clinical image
A 4-year-old child presented with multiple hyperpigmented and hypopigmented macules and plaques over both forearms, with a history of recurrent flaccid bullae and erosions at the same sites. Nikolsky sign was positive during the active phase. Tzanck smear showed acantholytic cells, and skin biopsy revealed intraepidermal acantholysis. Direct immunofluorescence demonstrated intercellular deposition of IgG and C3 in a fish-net pattern, confirming the diagnosis. The child was treated with systemic corticosteroids and azathioprine, leading to disease control. The present image shows the healing phase with post-inflammatory dyspigmentation and residual scarring, highlighting chronic sequelae of pediatric pemphigus vulgaris, a rare condition in this age group.

Corresponding Author

Sahil Vihirkar, Department of Child Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing Sawangi (Meghe), Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India (sahilvihirkar2000@gmail.com)

Article Formats

Articles published in Pan African Medical Journal are Open Access and distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0).

Open Access Logo

The Pan African Medical Journal (ISSN: 1937-8688) is a product of the PAMJ. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.