A 48-year-old man with a history of alcohol-related acute pancreatitis presented with sudden, severe abdominal pain radiating to the back. He reported drinking six cans of beer daily (10.7 UK alcohol units) for over 20 years. Nineteen days earlier, he sustained blunt trauma to his left flank while lifting a heavy generator. Abdominal computed tomography (CT) at another hospital revealed a hemorrhagic pancreatic cyst, and he was transferred to our institution. Laboratory tests revealed normocytic anaemia with normal amylase, lipase, and carbohydrate antigen 19-9 levels. On day three of hospitalisation, his haemoglobin dropped from 14 g/dL to 9.6 g/dL, and a periumbilical ecchymosis appeared (Panel A). Repeat CT demonstrated rupture of the hemorrhagic pancreatic cyst with hemoperitoneum (Panel B). Diagnostic paracentesis confirmed bloody ascitic fluid (SAAG = 0.4). He was managed conservatively with blood transfusion and tranexamic acid, and was discharged after five days in stable condition. The periumbilical ecchymosis represents the Cullen sign, a rare clinical finding first described in 1918, caused by blood tracking from the peritoneal cavity to the umbilicus via the falciform ligament. Although classically associated with hemorrhagic pancreatitis, the Cullen sign may also be seen in ruptured ectopic pregnancy, ruptured abdominal aortic aneurysm, and hepatocellular carcinoma rupture. In this patient, the Cullen sign resulted from rupture of a hemorrhagic pancreatic pseudocyst, likely precipitated by previous trauma.

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Corresponding author
Yoen Young Chuah, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Ping Tung Christian Hospital, Ping Tung, Taiwan (yoenyoungchuah@gmail.com)