Fluoroquinolone-induced generalised fixed drug eruption: a rare clinical image

Fluoroquinolones are commonly used antimicrobial agents in patients presenting with respiratory diseases with levofloxacin, ofloxacin, and moxifloxacin having a significant role in the management of pulmonary tuberculosis and atypical pneumonia. However, the use of fluoroquinolones is also associated with the development of adverse drug reactions such as tendon rupture, Qtc interval prolongation, and generalised drug eruptions. Here we present to you a 70-year-old male patient who presented with generalised drug eruption rash over the body 3 days after starting levofloxacin therapy for atypical pneumonia. The patient was treated as per the dermatologist´s advice with oral corticosteroids and antihistaminics. After 7 days significant improvement was noted in skin eruptions. This clinical image aims to highlight a rare adverse effect of a commonly used antimicrobial agent.