A rare clinical image of frontal hemorrhagic metastasis in chronic myelogenous leukaemia patient

Pradhyum Dilip Kolhe, Sharath Hullumani

PAMJ. 2025; 50:3. Published 02 Jan 2025 | doi:10.11604/pamj.2025.50.3.45836

A 41-year-old male patient was brought to hospital casualty by his relatives with complaints of altered sensorium and reduced consciousness. He had a history of one episode of convulsions, involuntary movements of bilateral upper limb and lower limb. No history of bowel and bladder complains. He had a known case of chronic myelogenous leukaemia for which he took chemotherapy in the past 4 years. Patient was intubated in casualty. Diagnostic evaluations including an magnetic resonance imaging (MRI) scan, have substantiated a diagnosis of hemorrhagic metastasis in the right frontal region. The figure revealed the presence well, defined heterogeneously enhancing T2 hyperintense lesion with edema is seen in right precentral gyrus measuring 13x11 mm in size metastases. A well-defined area of blooming appearing hypointense on T2 is seen in right frontal lobe known as acute hematoma metastases. Acute hematoma is seen in right basal ganglia measuring 12x8mm in size with possible extension into bilateral, 3rd and 4th ventricle. Moderate dilatation of bilateral 3rd and 4th ventricle noted with periventricular chronic fatigue syndrome (CSF) leak. Mass effect is seen inform of midline shift of 8 mm towards left side. Patchy areas of diffusion restriction are seen in parasaggital cortex of frontoparietal lobe and body of corpus callosum likely acute infarct in bilateral anterior cerebral artery (ACA).
Corresponding author
Sharath Hullumani, Department of Paediatric Physiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Higher Education and Research (DU) Sawangi Meghe, Maharashtra, India (sharathhullumani@gmail.com)


The Pan African Medical Journal (ISSN: 1937-8688) is a subsidiary of the Pan African Medical Journal. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.

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