Post tubercular bronchiectasis with aspergilloma

Ashwin Karnan

PAMJ. 2024; 48:68. Published 26 Jun 2024 | doi:10.11604/pamj.2024.48.68.43859

A 48-year-old diabetic male, presented to the outpatient department with complaints of fever, breathlessness on exertion, and cough with mucopurulent expectoration for the past 15 days. The patient gave a history of pulmonary tuberculosis 4 years back for which he took antitubercular therapy for 6 months. CT thorax showed a cavity with a hypodense lesion and cystic bronchiectatic changes in the left lower lobe. Echocardiography showed a dilated right ventricle with pulmonary arterial hypertension. Sputum for acid-fast bacilli was negative, serum IgG antibody for Aspergillus was raised and Bronchoalveolar lavage galactomannan was positive confirming the diagnosis of Aspergilloma. The patient was treated with Voriconazole, phosphodiesterase-5-inhibitor, oral corticosteroids, oral hypoglycemic agents, and diuretics. The patient improved symptomatically and is currently on follow-up. Aspergillus colonization usually occurs in a previously existing lung cavity. Aspergilloma may be difficult to diagnose due to its complexity. It has around 38% mortality rate. Hemoptysis is the dreaded complication requiring bronchial artery embolization.
Corresponding author
Ashwin Karnan, Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India (ashwin2700@gmail.com)

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