|
Table 2: factors associated with the death of patients hospitalized in intensive care for infection with the influenza A virus |
||||
|
|
Total (n=40) |
Survivors (n = 18) |
died (n=22) |
p |
|
Characteristics of the population |
|
|
|
|
|
Age (Med, IQR 25-75) |
48(17-76) |
49(27-79) |
53.5 (17-76) |
0.54 |
|
Male, n (%) |
24(61.5) |
12(70.5) |
12(54.5) |
0.20 |
|
Pregnancy, n (%) |
2(5) |
0(0) |
2(9) |
- |
|
IMC >30 (kg/m2) |
12(30.7) |
2(11) |
10 |
0.02* |
|
Comorbidities, n (%)
|
|
|
|
|
|
Chronic lung disease |
10(25) |
5(27) |
5(23) |
0.43 |
|
Diabetes |
13(32) |
7(38) |
6(27) |
0.15 |
|
Cardiovascular |
12(30) |
5(27) |
7(32) |
0.60 |
|
Obesity
|
12(30)
|
2(11)
|
10(45)
|
0.02*
|
|
Severity Score |
|
|
|
|
|
SAPSII (Med, IQR 25-75) |
29(6-66) |
26(6-32) |
36.95(28-50) |
<10-3* |
|
SOFA (Med, IQR 25-75) |
6(3-10) |
3(0-6) |
9(4-16) |
<10-3* |
|
Failure of Organ |
|
|
|
|
|
Hémodynamique, n (%) |
13(33.3) |
2(11) |
11(50) |
0.01* |
|
Rénale, n (%) |
6(15) |
1(5) |
5(23) |
0.14 |
|
SDRA (P/F<200), n(%) |
22(56.4) |
3(17.6) |
19(86.3) |
<10-3* |
|
Données biologiques (Med, IQR 25-75) |
|
|
|
|
|
Creatinine (µmol/l) |
90.5 (47-620) |
90(64-215) |
91(47-620) |
0.09 |
|
Plates (103élts/mm3) |
180(56-497) |
180(56-497) |
180(71-462) |
0.55 |
|
CRP (mg/l) (Med, IQR 25-75) |
126.5 (3.5-488) |
39(3-488) |
180(42-337) |
0.01* |
|
Glycemia (mmol/l) (Med, IQR 25-75) |
12(7.11-16.25) |
11(6.20-16) |
12(6.20-18.20) |
0.51 |
|
Uremia (mmol/l) (Med, IQR 25-75) |
8(5.40-18) |
10(6.30-16) |
14(8.50-22) |
0.48 |
|
Traitement, n(%) |
|
|
|
|
|
corticosteroids |
17(43.5) |
5(29.4) |
12(54.5) |
0.08 |
|
oseltamivir |
21(52.5) |
9(50) |
12(54.5) |
0.45 |
|
catecholamines |
24(60) |
5(28) |
19(86) |
0.004* |
|
Duration VM (Med, IQR 25-75) |
4(2-7) |
7.57 (2-14) |
5.55 (1-11) |
0.48 |
|
Nosocomial infection, n (%) |
8(20) |
0(0) |
8(36) |
0.014* |
|
ARDS, acute respiratory distress syndrom; SOFA, Sepsis-related Organ Failure Assessment; SAPSII, Simplified acute physiology score |
||||