Original article | Volume 21, Article 82, 02 Jun 2015 | 10.11604/pamj.2015.21.82.5833

Giant adenoid cystic carcinoma of the sinonasal cavity

Mohamed Mliha Touati, Haddou Ammar

Corresponding author: Mohamed Mliha Touati , ENT Department, Military Hospital Avicenna, Marrakech, Morocco

Received: 26 Nov 2014 - Accepted: 01 Dec 2014 - Published: 02 Jun 2015

Domain: Clinical medicine

Keywords: Sinonasal cavity, adenoid cystic carcinoma, ethmoïdomaxillonasal tumor

©Mohamed Mliha Touati et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Mohamed Mliha Touati et al. Giant adenoid cystic carcinoma of the sinonasal cavity. Pan African Medical Journal. 2015;21:82. [doi: 10.11604/pamj.2015.21.82.5833]

Available online at: https://www.panafrican-med-journal.com/content/article/21/82/full

Home | Volume 21 | Article number 82

Original article

Giant adenoid cystic carcinoma of the sinonasal cavity

Giant adenoid cystic carcinoma of the sinonasal cavity

 

Mohamed Mliha Touati1, &, Haddou Ammar1

 

1ENT Department, Military Hospital Avicenna, Marrakech, Morocco

 

 

&Corresponding author
Mohamed Mliha Touati , ENT Department, Military Hospital Avicenna, Marrakech, Morocco

 

 

Image in medicine

Adenoid cystic carcinomas, formerly known cylindromas, were originally described by Foote and Frozell 1953. These are epithelial malignancies that develop at the expense of salivary glands, other rare localizations have been described in particular in the oral cavity, the sinonasal tract, lacrimal glands or nasopharynx. Clinical and radiological signs are not specific, and are common to all sinonasal tumors, including squamous cell carcinomas and adenocarcinomas. The adequate treatment is surgery, postoperative radiation therapy improves long-term prognosis. These tumors are characterized by aggressiveness and a high incidence of local recurrence and distance metastasis regardless of therapeutic modalities used. We report a case of a 70 year old patient, hospitalized for exploration of a large sinonasal tumors, CT Scann of the face and sinonasal cavities disclosed a large right ethmo´domaxillonasal tumor, with tissue density with and contrast enhancement, lysing all the walls of the maxillary sinus, septum and the horizontal branch of the mandible. With extension to the infratemporal fossa, the orbital floor, the contralateral nasal cavity, the floor of the nasal cavity and nasopharynx. A nasal biopsy concluded to an adenoid cystic carcinoma, The staging revealed no distant metastases, the tumor was classified T4NoMo.The patient refused any surgery, he was referred for palliative radiotherapy, it was lost sight of.

 

 



Figure 1: (A): computed tomography of the sinonasal area, axial section with contrast medium injection,showing a tumor process the right maxillary sinus with extension to the nasal cavity and the infatemporale fossa and bone erosion, (B) : computed tomography of the sinonasal area, coronal section showing a large ethmoidomaxillar tumor process extended to the nasal cavity with lysis of intersinusonasal wall and nasal septum, (C) : adenoid cystic carcinoma: cribriform lobules composed of somewhat irregular cells scattered in a fibrohyaline stroma. HE x100

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Original article

Giant adenoid cystic carcinoma of the sinonasal cavity

Original article

Giant adenoid cystic carcinoma of the sinonasal cavity

Original article

Giant adenoid cystic carcinoma of the sinonasal cavity