Correlation of neck circumference with other anthropometric measurements among participants in a market survey at Ebonyi, South East, Nigeria

¹Department of Medicine, Alex-Ekwueme Federal University Ndufu- Alike Ikwo, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Ebonyi state, ²College of Medicine, Enugu State University Teaching Hospital, Parklane, Enugu, ³College of Health Sciences, Nnamdi Azikiwe University Awka, Anambra State, ⁴Department of Medicine, Ebonyi State University, Abakaliki, Ebonyi state, ⁵Department of Nursing Sciences, David Umahi Federal University of Health Sciences, Uburu, Ebonyi state

^&Corresponding author
Chidiebere Valentine Ugwueze, Department of Medicine, Alex-Ekwueme Federal University Ndufu- Alike Ikwo, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Ebonyi state

Introduction    

Obesity is a chronic metabolic disease arising from excessive intake of calories in excess of consumption resulting in unhealthy and excessive fat deposition in different parts of the body. Obesity was initially considered a serious concern in developed nations of the world but unfortunately, it is becoming a worrisome condition in developing countries [1]. In 2022, about 43% of adults aged 18 years and above were overweight and 16% (890 million) persons were living with obesity according to the World Health Organization (WHO) fact sheet, 2024 [1]. Systematic studies in Nigeria reported the prevalence of obesity as ranging from 8.1 to 22.2 [2,3]. In sub-Saharan Africa, a comparative study which involved women of reproductive age, the prevalence of obesity was estimated as: South Africa (36%), Mauritania (27%), Eswatini (23%), Lesotho (20%), Gabon (19%) and Ghana (15%) [4]. A pooled study by Non-Communicable Disease Risk Factor Collaboration (NCD-RisC), Africa Working Group from 1980 to 2014 reported that the mean BMI increased from 21.0kg/m² to 23.0kg/m² in men and from 21.9kg/m² to 24.9kg/m² in women which describes an upward trend [5]. There was an increased BMI in all the regions involved in the study. Though obesity was initially regarded as a manifestation of healthy living [6,7], there are many complications arising from obesity including hypertension, diabetes mellitus, osteoarthritis, poor wound healing, respiratory diseases, and cancers [8,9]. Due to the multiple effects of obesity, the latter is considered to have a public health importance. In the evaluation of obesity, various anthropometric measurements are in use for sometimes and they include: body mass index, waist circumference, hip circumference, and waist-to-hip ratio [10,11]. Neck circumference is among the newer measures being considered [12].

Neck circumference as a measure of obesity is easier and may not necessarily involve exposing a larger part of the body. Neck circumference as a measure of obesity is easily adapted to the patient as it is less cumbersome. Neck circumference is an indicator of subcutaneous fat in the upper regions of the body and also a predictor of cardiovascular risk as reported by Kim et al., and Ataie -Jafari et al. [13,14]. Many authors have reported a strong correlation between neck circumference and waist circumference in patients with prediabetes and diabetes [12,15,16]. A review of anthropometric indices among 133 healthy persons by Omozehio et al. [17] showed a significant positive correlation between neck circumference and WC, HC, and BMI (Pearson´s correlation, r=0.62, 0.65, 0.66 respectively). Similar findings were obtained by other authors [18,19]. The correlation of neck circumference (NC) with WC, HC, and BMI was stronger in males than in females [17,20]. The mean neck circumference in different studies were: 40.45 ± 2.68 cm for men and 32.71 ± 2.37 cm for females [20], 38.9 ± 3.2 cm for men and 35.4 ± 3.1 cm [21], 38.9 cm for men and 36 cm for women [22]. Sruthi et al. [23] opined that among Indians, a neck circumference of more than 35.5cm in men and more than 32 cm in women should be considered obesity. High neck circumference is a predictor of hypertension and obstructive sleep apnea as revealed by Ren et al. [24] and Cao et al. [25] respectively. Furthermore, in assessment of insulin resistance, neck circumference was shown to be a better anthropometric parameter than waist circumference [26-28]. It has also been demonstrated that NC was a better predictor of glucose homeostasis and HDL-Chol concentrations when compared to BMI and WC [28]. This study was set out to determine the prevalence of obesity and the correlation between neck circumference and BMI, waist circumference, hip circumference, and waist-to-hip ratio among participants.

Methods     

Study design and setting: it is a cross-sectional and descriptive study. The study was carried out at Margret Umahi International Market, Abakaliki, Ebonyi state. It is the most prominent market in Ebonyi state and attracts traders from adjoining states such as Cross River state.

Study population: the study participants consisted of 197 individuals who consented to the study. The participants were mainly traders and other individuals of different professions who attended the market on the day of the study.

Inclusion criteria: individuals aged above 18 years and; ii)individuals who gave consent to participate in the study.

Exclusion criteria: individuals who did not consent to the study; ii) those who are pregnant.

Sampling technique: convenience sampling technique was used as participants were recruited as they presented to the study venue.

Procedure and data collection: the weight of participants were measured with the weighing scale of a stadiometer (Seca; Steindham, Hamburg- Germany, 2013). The stadiometer was used to obtain the height. Body mass index was calculated as weight in kilograms divided by height in meters squared (kg/m²). The neck, waist circumference, and hip circumference of participants were measured with a stretchable measuring tape.

Neck circumference: a stretchable measuring tape was placed on a horizontal plane at the lower edge of the cricoid cartilage while the participant is to look forward directly in front [20]. A measuring tape is wound around the neck between the mid-anterior neck (the most prominent portion of thyroid cartilage) and mid-cervical spine to obtain the neck circumference [20]. The waist circumference was obtained with a stretchable measuring tape wound around the midway between the last palpable rib and iliac crest [29]. The hip circumference was obtained as the widest circumference around the gluteus maximus.

Statistical analysis: the data obtained from the study was analyzed using the Statistical Package for Social Sciences SPSS (IBM-SPSS) for Windows version 23 (IBM, Corp., Armonk N.Y., USA). The characteristics of participants were summarized using descriptive statistics. The prevalence was calculated as frequencies and percentages as shown in Table 1. Pearson´s correlation was used to assess the correlation between neck circumference and other anthropometric measurements as shown in Table 2. Similarly, the correlation of blood pressure with different anthropometric measurements involved the use of Pearson´s correlation. A significant correlation was defined by p-values ≤ 0.05. Student- t-test was used to compare the mean neck circumference of male and female participants as in Table 3.

Ethical consideration: an ethical clearance for the study was obtained from the Ethics and Research Committee of the Alex-Ekwueme Federal University Teaching Hospital, Abakaliki with an Ethical Clearance number: AE-FUTHA/REC/VOL3/2022/087. Informed consent was obtained from the participants and were allowed to withdraw at any time in the study without any negative impact on their treatment. This study adhered to the STROBE guidelines for observational research, ensuring transparency and robustness in study design, data collection, and reporting.

Results     

Demographic characteristics: the study participants were 197: 104 males and 93 females. The participants were traders (51.8%), civil servants (18.3%), farmers (8.6%), drivers (5.6%), students (4.6%), health workers (2.5%) and others (8.6%) respectively. The average age of the subjects was 41.8 ± 16.3 years.

Prevalence of obesity: the prevalence of obesity among the participants was 17.8% which comprised of (Class 1 obesity 11.2%, class 2 obesity 5.1%, and morbid obesity 1.5%) as shown in Table 1. Using the waist-hip ratio (WHR), the prevalence of central obesity was 26.9% among the participants (Table 1). Correlation of neck circumference and other parameters. The correlation of neck circumference with other measures of obesity was highly significant: for BMI (p< 0.001, r =0.291), waist circumference (p< 0.001, r= 0.804), hip circumference (p < 0.001, r= 0.846) and WHR (p< 0.001, r=0.337) as shown in Table 2. The mean of different anthropometric measurements were: BMI (25.5 ±5.2 kg/m²), waist circumference (88.1±14.1 cm), Hip circumference (100.4±11.5), Waist - hip ratio (0.88 ± 0.1) and neck circumference (36.4 ± 4.7 cm). The mean neck circumference for males and females was 38.0cm and 34.5cm respectively. The mean neck circumference for males was significantly different from that of females (p< 0.001). as shown in Table 3. The systolic and diastolic blood pressures correlated positively with neck circumference and all other measures of obesity with highly significant p- p-values (Table 4).

Discussion     

The study aimed at determining the prevalence of obesity as well as correlating neck circumference with other anthropometric parameters. The results revealed the prevalence of overweight and obesity as 34% and 17% respectively (Table 1). The prevalence of obesity obtained using waist circumference was higher than that of BMI. Moreover, the neck circumference correlated significantly and positively with other anthropometric parameters. The implication of the prevalence of overweight and obesity from this study is that it is a common metabolic problem. The study population consisted of mainly traders who may not adhere to routine healthy eating and physical exercise regimens, thus giving rise to a high prevalence of obesity. This is similar to the finding of a systematic review by Chukwunonye et al. [2] who reported the prevalence of overweight among Nigerian men and women as 26.3% and 28.3% respectively while the prevalence of obesity was 10.9% and 23.0% respectively. Similarly, a higher prevalence of obesity obtained using waist circumference compared to BMI has also been substantiated by Shrestha et al. [30]. Central obesity is usually considered to have poorer health outcomes than generalized obesity [31]. This is because of the degree of inflammation initiated by central adiposity. Thus, the use of waist circumference to determine central obesity is usually adopted by most researchers rather than BMI. The limitation of BMI is the difficulty in distinguishing weight contributed by muscles, fats, and bone density [32].The neck circumference from this study was shown to have a significantly positive correlation with all the other standard obesity measurements (Table 2). The reason for the positive correlation is due to the corresponding accumulation of subcutaneous fat in the neck as fats also accumulate in other areas of the body in obese patients. This is similar to the findings of Omozehio et al. and Qureshi et al. [17,19] Omozehio et al. [17] demonstrated a significantly positive correlation between neck circumference and other anthropometric parameters such as waist circumference, hip circumference, and BMI.

The mean NC of males and females in this study was 38 cm and respectively as shown in Table 3. The finding is similar to the findings of Olusola et al. [22] in South Western, Nigeria. However, there was a slight difference between the findings in this study and that of Ukoha et al. [20] even though higher values were still noted in males. The predominantly higher NC in males compared to females has been substantiated in many studies [33,34]. The gender difference is related to the soft tissue mass and fat deposits in the neck which has been shown to be higher in males than in females using magnetic resonance imaging [35]. Men with NC > 37 cm and women with NC > 34 cm are more prone to cardio-metabolic syndrome and require more evaluation [36]. The correlation of blood pressure with neck circumference and other obesity measurements was significant as shown in Table 4. This was also similar to the findings of Ren and colleagues, [24] who demonstrated that higher neck circumference predicted hypertension in about 42 % of study subjects. Alfadhli et al. [37] also demonstrated the positive correlation of neck circumference with systolic blood pressure in both males and females and between NC and diastolic blood pressure in men but not in women. Similarly, Ramoshaba et al. [38] have equally demonstrated among 127 students aged from 18 years and above that NC significantly correlates with both systolic (r=0.5; p< 0.001) and diastolic blood pressures ( r=0.3; p < 0.001) using Pearson´s correlation analysis. Makaju et al. [39] in a study among 1000 Nepalese patients attending Manipal Teaching Hospital showed a similar correlation of NC with both systolic and diastolic blood pressure but the correlation was more positive with diastolic blood pressure among female participants taking antihypertensive medication.

The explanation for the correlation of neck circumference and blood pressure is that central obesity as reflected by increased neck circumference gives rise to the release of some inflammatory cytokines such as tumor necrosis factor-α and IL-6. The cytokines can cause vascular endothelial dysfunction leading to increased vascular resistance and elevated blood pressure [40]. Moreover, obesity as manifested by increased neck circumference brings about an increase in sympathetic nervous system activity which elevates heart rate, total peripheral resistance, and blood pressure [41]. The limitation of this study is that it is a one-centre study which may limit the validation of the findings and will require multiple-centre studies for better validation. The conducting of this study in a market area makes the study population a good representation of the society. The correlation of neck circumference with more than one anthropometric measurement adds strength to the study.

Conclusion     

The importance of neck circumference as a measurement for obesity assessment cannot be over-emphasized. The significant correlation of NC with other anthropometric measurements makes it very reliable and efficient in the management of patients with obesity. Furthermore, the correlation of neck circumference with blood pressures makes former an invaluable tool in the management of hypertension and obesity.

Competing interests     

The authors declare no competing interest.

Authors' contributions     

Conception and study design: Chidiebere Valentine Ugwueze. Data collection: Chinweuba Michael Abonyi, Kenechukwu Emmanuel Onyekachi and Nnamdi Chukwunomso Anikpo. Data analysis and interpretation: Chidiebere Valentine Ugwueze, Basil Chukwuma Ezeokpo, ,Thomas Obiora Nnaji. Manuscript drafting: Chidiebere Valentine Ugwueze, Chinweuba Michael Abonyi, Collins Nnachi Ugwu, Manuscript revision: Maris Unoma Ugwueze, Chidiebere Valentine Ugwueze, Kenechukwu Emmanuel Onyekachi, Nnamdi Chukwunomso Anikpo, Nneka Chika-Igwenyi, Basil Chukwuma Ezeokpo. Guarantor of the study: Chidiebere Valentine Ugwueze. All the authors have read and agreed to the final manscript.

Tables and figures     

Table 1: prevalence of obesity among participants

Table 2: correlation of neck circumference with standard obesity measurements

Table 3: comparison of mean neck circumference of males with that of females

Table 4: correlation of blood pressure with standard obesity measurements

References