Snake bite - cytotoxic effects of snake venom: a rare clinical image
Lalrintluangi Royte, Achita Sawarkar
Corresponding author: Lalrintluangi Royte, Department of Community Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, Maharashtra, India
Received: 11 Oct 2022 - Accepted: 21 Jan 2023 - Published: 01 Feb 2023
Domain: Nursing education
Keywords: Cytotoxic, snake bite, snake venom, envenomation, tissue necrosis
©Lalrintluangi Royte et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Lalrintluangi Royte et al. Snake bite - cytotoxic effects of snake venom: a rare clinical image. Pan African Medical Journal. 2023;44:61. [doi: 10.11604/pamj.2023.44.61.37759]
Available online at: https://www.panafrican-med-journal.com//content/article/44/61/full
Snake bite - cytotoxic effects of snake venom: a rare clinical image
Lalrintluangi Royte1,&, Achita Sawarkar1
&Corresponding author
Venoms of cobras contain high abundances of cytotoxins, which contribute to tissue necrosis in cobra envenomation. Cyto refers to cells, and cytotoxicity broadly describes a toxic effect on cell function. Cytotoxic activity can lead to edema (fluid retention), severe blistering, apoptosis (cell death), and necrosis. As the name suggests, cytotoxic venom kills cells. This venom is not as deadly as hemotoxic or neurotoxic venom. However, secondary injuries such as loss of limb function and other disabilities often result from cytotoxic venom. A 38-year-old male was brought to out-patient department with a complaint of necrotic tissue on the right side of the dorsal hand and wrist which results from an untreated snake bite roughly for about one week. Physical examination was performed by the physician which shows severe local tissue damage on the wrist and dorsal part of the right hand. Necessary treatments were given and the patient was referred to the medicine department for further management.
Figure 1: damaged tissue on the dorsal hand