Osteomalacia: a forgotten diagnosis of multiple bone fractures
Karim Khezami, Mohamed Amine Bennou
Corresponding author: Karim Khezami, Faculty of Medicine of Tunis, University Tunis El Manar, Department of Orthopedic Surgery, Habib Bougatfa Hospital, Bizerte, Tunisia
Received: 21 Mar 2021 - Accepted: 01 Apr 2021 - Published: 15 Apr 2021
Domain: Rheumatology
Keywords: Osteomalacia, femoral neck, fracture
©Karim Khezami et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Karim Khezami et al. Osteomalacia: a forgotten diagnosis of multiple bone fractures. Pan African Medical Journal. 2021;38:369. [doi: 10.11604/pamj.2021.38.369.28987]
Available online at: https://www.panafrican-med-journal.com//content/article/38/369/full
Osteomalacia: a forgotten diagnosis of multiple bone fractures
Karim Khezami1,&, Mohamed Amine Bennour1
&Corresponding author
We present a case of a 53-year-old female patient with chronic anemia, with no other significant medical history and on no regular medications. The patient was brought to the accident and emergency department following found on the floor of her home after having tripped over a mat and henceforth being unable to mobilize and complaining of pain in her bilateral hip and her right leg. X-rays confirmed bilateral neck of femur fractures and fracture of the distal end of the tibia and fibula. The bones were extremely gracile and osteoporotic. Investigations demonstrated raised parathyroid hormone levels (199 pg/mL, normal range (nr) 15-72), with low vitamin D (7 ng/mL, nr 50-100) and adjusted calcium (1.87 mmol/L, nr 2.2-2.6) levels. We have eliminated the diagnosis of myeloma. Calcium and vitamin D were replaced prior to the insertion of bilateral femoral nails.
Figure 1: A) bilateral proximal femoral fractures associated with low energy; B) right subtrochanteric femoral fracture; C) left subtrochanteric femoral fracture; D) diffuse demineralization of the spine: osteoporotic-like pattern; (E,F) supramalleolar fracture of tibia and fibula