La cyclopie, maformation rare du visage dans un centre de santé de référence de Bamako à propos d'un cas

Cyclopia also called "cyclopia" is a rare genetic malformation. It is the most severe form of alobaric holoprosencephaly. It is a rare form of hypotelorism characterized by the fusion of the two orbits and the presence of a single eye in the middle of the forehead hence its name. This malformation is associated with other facial malformations. Cyclopia is related to the absence of development of the frontal bud returning within the scope of ectroprosopia. ormation, face. We report a case of cyclopia in a newborn female born from a pregnancy estimated at term. The delivery was dystocic and the mother did not attend any prenatal consultations. The interrogation does not find any bond of consanguinity of the parents of the newborn. Absence of malformation in the siblings which is composed of four hildrens. At birth, the newborn weighed 4600 grams with a height of 58 cm. The examination of the newborn revealed a malformation of the face with a large single eye in the middle of the forehead and a total absence of the nose and orbits evoking the diagnosis of a cyclopia. The newborn died about ten minutes after his birth. He stayed alive just a few minutes. No further exploration for etiological purposes could be carried out because of the parents' refusal.

Key words: Cycolopia, malformation, frontal bud