Invasive hydatidiform mole in the cervix
Houssine Boufettal, Naïma Samouh
Corresponding author: Houssine Boufettal, Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc
Received: 05 Sep 2016 - Accepted: 31 Oct 2016 - Published: 12 Jan 2018
Domain: Clinical medicine
Keywords: Invasive mole, cervix, gestational trophoblastic tumor, chemotherapy
©Houssine Boufettal et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Houssine Boufettal et al. Invasive hydatidiform mole in the cervix. Pan African Medical Journal. 2018;29:27. [doi: 10.11604/pamj.2018.29.27.10675]
Available online at: https://www.panafrican-med-journal.com//content/article/29/27/full
Invasive hydatidiform mole in the cervix
Houssine Boufettal1,&, Naïma Samouh1
1Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc
&Corresponding author
Houssine Boufettal, Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc
A patient aged 43-years, multiparous consulted for uterine bleeding of average abundance. The examination revealed a burgeoning lesion of the cervix, which came from the uterine endocervix, measuring two centimeters. The uterus was increased in size measuring 88 mm long and 67 mm in anteroposterior diameter. There were no adnexal mass. Pelvic ultrasound showed a heterogeneous snowflake mass measuring 29 mm in anteroposterior diameter. Beta-h-CG (human chorionic gonadotrophin) quantitative plasma were highly increased to 854212 IU / ml. Histological study of aspirate objectified a complete hydatidiform mole. The staging featuring a thoraco-abdominopelvic CT scan, chest radiography, ultrasound abdomen and pelvis was normal. Pathological examination of the hysterectomy piece objectified an invasive mole to cervical and uterine location. A methotrexate-based agent chemotherapy was introduced. The evolution was marked by the gradual decline of the mass until it disappearance within four months. Plasma beta-h-CG had regressed and were normalized after two months of treatment. The outcome was favorable. With a follow-up of 24 months, no recurrence was noted.
Figure 1: pathological examination of the hysterectomy piece objectified an invasive mole in cervical spine (arrow) and uterine