Specific cutaneous involvement in a child with monoblastic leukemia
Siham Cherkaoui, Said Benchekroun
Corresponding author: Siham Cherkaoui, Department of Hematology and Pediatric Oncology, hospital 20 Août1953, Ibn Rochd University hospital, Casablanca, Morocco 
Received: 14 Apr 2013 - Accepted: 03 May 2013 - Published: 22 Apr 2014
Domain: Clinical medicine
Keywords: Monoblastic leukemia, fine needle aspiration, splenomegaly
©Siham Cherkaoui et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Siham Cherkaoui et al. Specific cutaneous involvement in a child with monoblastic leukemia. Pan African Medical Journal. 2014;17:307. [doi: 10.11604/pamj.2014.17.307.2726]
Available online at: https://www.panafrican-med-journal.com//content/article/17/307/full
Original article 
Specific cutaneous involvement in a child with monoblastic leukemia
Specific cutaneous involvement in a child with monoblastic leukemia
Siham Cherkaoui1,&, Said Benchekroun1
1Department of Hematology and Pediatric Oncology, hospital 20 Août1953, Ibn Rochd University hospital, Casablanca, Morocco
&Corresponding author
Siham Cherkaoui, Department of Hematology and Pediatric Oncology, hospital 20 Août1953, Ibn Rochd University hospital, Casablanca, Morocco
A 13-year-old boy, admitted with hemorrhagic syndrome and fever. Physical exam showed dermo-hypodermic nodular lesion on the whole body (figure 1), facial edema (figure 2), splenomegaly at 2 cm and angulo mandibular lymph node of 2cm. Count blood cells found white blood cell at 1360/mm3 with 94% of blasts, anemia at 8.3 g/dl and thrombocytopenia at 38000/mm3. Morphological examination of bone marrow confirmed diagnosis of acute monoblastic leukemia. Flow cytometry showed positivity of CD11c, CD13, CD33, CD34, HLA-DR. karyotype was normal. Child received chemotherapy.
Figure 1: A) Cutaneous nodules; B) Facial edema
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