Hyperpigmented mycosis fungoides: a rare variant
Meryem Soughi, Fatima Zahra Mernissi
Corresponding author: Meryem Soughi, CHU HAssan 2, Fes, Morocco
Received: 04 May 2013 - Accepted: 07 May 2013 - Published: 07 May 2013
Domain: Clinical medicine
Keywords: mycosis fungoides, skin biopsy, photoprotection
©Meryem Soughi et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Meryem Soughi et al. Hyperpigmented mycosis fungoides: a rare variant. Pan African Medical Journal. 2013;15:13. [doi: 10.11604/pamj.2013.15.13.2789]
Available online at: https://www.panafrican-med-journal.com//content/article/15/13/full
Hyperpigmented mycosis fungoides: a rare variant
Meryem Soughi1,&, Fatima Zahra Mernissi1
1CHU HAssan 2, Fes, Morocco
&Corresponding author
Meryem Soughi, CHU HAssan 2, Fes, Morocco
Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. The diagnosis of classic MF is based on a combination of clinical presentation, histopathology, immunohistochemistry, and T-cell monoclonality detected by molecular studies. However, the diagnosis can be difficult in some cases. We report a case of hyperpigmented mycosis fungoides. A 60-year-old woman, phototype IV, presented for more than 4 years a history of asymptomatic hyperpigmented non- infiltrated plaques on the face. Cutaneous lupus was diagnosed based on a skin biopsy. Hydroxychloroquine and photoprotection was started. Considering non improvement, another biopsy was done, in favor of a mycosis fungoides CD3+, CD4+, CD8-. The diagnostic of hyper pigmented mycosis fungoides stage I was retained and topical steroid was introduced. Mycosis fungoides can appear in various clinical forms, the hyperpigmented form is rare but this diagnosis should be evoked.
Figure 1: pigmented plaques of the nasolabial fold and the chin