Mirroring spinal cord lesion secondary to B12 deficiency
Youssouf Benmoh, Ahmed Bourazza
The Pan African Medical Journal. ;26:130. doi:10.11604/pamj..26.130.11853

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Mirroring spinal cord lesion secondary to B12 deficiency

Youssouf Benmoh, Ahmed Bourazza
Pan Afr Med J. 2017; 26:130. doi:10.11604/pamj.2017.26.130.11853. Published 07 Mar 2017



A 26 year-old girl, previously healthy, admitted for progressive weakness of both lower limbs, with permanent paresthaesia evolving for 6 months. Clinical examination found spastic paraparesis with proprioceptive ataxia. The MRI showed bilateral and symmetrical lesions in the cervical spinal cord. Lesions were T1-isointense and T2 hyperintense, located on both lateral and posterior funiculus without enhancement. Investigation revealed deep vitamin B12 deficiency (27pg/ml), macrocytosis, with positive parietal cell-antibody and fundic gastritis. Patient was treated with intra muscular hydorxycobalamin. Evolution was favorable with regression of weakness and parethaesia of both lower limbs, and persistence of discreet ataxia. Cobalamin deficiency is common in the elderly. It causes hematologic, digestive and neurological disorders. Neurological signs are dominated by combined sclerosis of the spinal cord, and peripheral neuropathy. MRI is useful in front of myelopathy, showing an enlargement or T2-hyperintense lesion of the posterior funiculus.


Corresponding author:
Youssouf Benmoh. Department of Neurology, Military Hospital MOHAMED V, Rabat, Morocco
youssouf1680@gmail.com

©Youssouf Benmoh et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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