Perihepatitis in systemic lupus erythematosus
Janet Laabidi, Faida Ajili
The Pan African Medical Journal. ;20:280. doi:10.11604/pamj..20.280.5534

Create an account  |  Sign in
PAMJ - Clinical Medicine PAMJ - Clinical Medicine
"Better health through knowledge sharing and information dissemination "

Images in clinical medicine

Perihepatitis in systemic lupus erythematosus

Janet Laabidi, Faida Ajili
Pan Afr Med J. 2015; 20:280. doi:10.11604/pamj.2015.20.280.5534. Published 23 Mar 2015

We report the case of a 42-year old male patient was admitted to our hospital because of a two weeks history of severe dry cough and right upper quadrant pain. He had been diagnosed as LES with diffuse proliferative lupus nephritis (class IV) in 2006 treated intially by intravenous steroid pulse therapy combined with an immunosuppressant and benefited in 2007 of Hemodialysis. In July 2013, he suffered of constant abdominal pain located at the right upper quadrant with dry cough. C-reactive protein (CRP) was 17 mg/L (normal < 8 mg/L) on admission with positive antinuclear antibodies title at 1/1280. The chest-abdominal computed tomography scan showed a pleural effusion a regular hepatomegaly with a rim of enhancement involving the right lobe of the liver. No ascites was present and there was no ancillary evidence of cholecystitis. The findings were thought to be most consistent with a perihepatitis. Pleural fluid examination showed an exudative pleural effusion with a negative culture. The diagnosis of perihepatitis associated with SLE complicated by a right pleural effusion was taken. The patient condition was treated with two antibiotics (vibramycin and amikacyn) and oral prednisolone. On review 4 weeks later his pain, cough and the right pleural disappeared. Perihepatitis is a rare disease, normally associated with pelvic inflammatory disease. It has rarely been reported in association with systemic lupus erythematosus (SLE) particularly in patients with lupus hemodialysis nephritis.

Corresponding author:
Faida Ajili, Department of Internal Medecine, Military Hospital of Tunis, 1008 Montfleury, Tunisie

©Janet Laabidi et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

More images in clinical medicine


PAMJ Images in Medicine and Public Health are archived on Pubmed Central. Access PAMJ archives on PMC here

Volume 34 (September - December 2019)

This image

Share this image:

Filter images [Reset filter]

By language

PAMJ is published in collaboration with the African Field Epidemiology Network (AFENET)
Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, Ulrichsweb, More to come . Member of COPE.

ISSN: 1937-8688. © 2019 - Pan African Medical Journal. All rights reserved