Congenital clitoromegaly in an adult
Mohammed Alae Touzani, Imad Ziouziou
The Pan African Medical Journal. 2019;34:141. doi:10.11604/pamj.2019.34.141.18149

AFRIKA K AFRIKA K
"Better health through knowledge sharing and information dissemination "

Images in medicine

Congenital clitoromegaly in an adult

Cite this: The Pan African Medical Journal. 2019;34:141. doi:10.11604/pamj.2019.34.141.18149

Received: 12/01/2019 - Accepted: 11/11/2019 - Published: 12/11/2019

Key words: Clitoris, clitoromegaly, 21 hydroxylase, pseudo-hermaphroditism

© Mohammed Alae Touzani et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/34/141/full

Corresponding author: Mohammed Alae Touzani, Department of Urology « B », Avicenne Hospital, Rabat, Morocco (medalaet@gmail.com)


Congenital clitoromegaly in an adult

Mohammed Alae Touzani1,&, Imad Ziouziou2

 

1Department of Urology « B », Avicenne Hospital, Rabat, Morocco, 2Department of Urology, Hassan II Hospital, Ibn Zohr University, Agadir, Morocco

 

 

&Corresponding author
Mohammed Alae Touzani, Department of Urology « B », Avicenne Hospital, Rabat, Morocco

 

 

Image in medicine    Down

Clitoromegaly is an abnormal enlargement of the clitoris. In adult, dimensional criteria are, according to Brodie, a minimum length hood and width of 27.4mm and 8mm. We here report the case of a 26 year female patient, with no previous personal history, who consults for primary amenorrhea with androgenization signs (hirsutism, deep voice…). Clinical examination showed a clitoromegaly and urogenital sinus persistency. The patient first underwent a karyotype that shows a female karyotype with no abnormalities (46,XX). Further explorations showed a 21-hydroxylase deficiency, with a congenital bilateral adrenal hyperplasia. Congenital adrenal hyperplasia (CAH) is defined by an increased size and metabolism of the adrenal glands due to enzymatic disorders, such as 21-hydroxylase deficiency. In women, this can lead to virilization of the external genitalia in 11% of patients, and a late diagnosis, such in this case, may result in the late discovery of androgenization signs, such as clitoromegaly. The treatment is clitoroplasty, which consist to reduce the clitoris size and preserve its sensitivity, with a vaginoplasty if there is an association with urogenital sinus persistency, if the patient is asking for it.

 

Figure 1: clitoromegaly with a "male glans" aspect

 

 

 

 

 

 

 

 

 

 

 

 


The Pan African Medical Journal articles are archived on Pubmed Central. Access PAMJ archives on PMC here

Volume 34 (September - December 2019)

Article tools

PDF (358 Kb)
Contact the corresponding author
Download to Citation Manager
EndNote
Reference Manager
Zotero
BibTex
ProCite


This article authors

On Pubmed
On Google Scholar

Navigate this article

Keywords

Clitoris
Clitoromegaly
21 hydroxylase
Pseudo-hermaphroditism

Rate this article

Altmetric

PAMJ is a member of the Committee on Publication Ethics
PAMJ Authors services
Next abstract

PAMJ is published in collaboration with the African Field Epidemiology Network (AFENET)
Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, Ulrichsweb, More to come . Member of COPE.

ISSN: 1937-8688. © 2019 - Pan African Medical Journal. All rights reserved