Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient
Salma Salim, Badreddine Hassam
The Pan African Medical Journal. 2019;34:108. doi:10.11604/pamj.2019.34.108.17999

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Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Cite this: The Pan African Medical Journal. 2019;34:108. doi:10.11604/pamj.2019.34.108.17999

Received: 21/12/2018 - Accepted: 16/02/2019 - Published: 23/10/2019

Key words: Buschke-L÷wenstein tumor, human papilloma virus, immunocompetent patient

© Salma Salim et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/34/108/full

Corresponding author: Salma Salim, Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco (salma-salim19@hotmail.fr)


Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Salma Salim1,&, Badreddine Hassam1

 

1Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco

 

 

&Corresponding author
Salma Salim, Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco

 

 

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We report the case of a 56-year-old man who presented with locally advanced giant condyloma acuminatum (Buschke-L÷wenstein tumor) after approximately 15 years of neglect due to hospital phobia. Clinical examination showed an extensive, erosive, exophytic and cauliflower-like growth involving his suprapubic, external genitalia and perianal region. No inguinal or supraclavicular lymphadenopathy was detected clinically. Histological study revealed a papillomatous and acanthotic epithelium with ortho and parakeratosis and koilocyte cells suggestive of HPV infection. No signs of malignant transformation were noted. Radiological investigations consisted of a thoracic-abdominal-pelvic computed tomography scan which showed the localization of this tumor in the external genitalia, perineal and suprapubic region without any lymph nodes or distant metastases. The results of biochemical and serological investigations including HIV test were normal. After discussion among the oncologist, radiotherapist, pathologist and surgeon, the patient initially received chemoradiotherapy, followed by extensive local excision with average outcome. Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It is a neoplasm of the anogenital region which has benign appearance on histopathology. It often grows over years in immunocompetent patients and can be highly destructive to local tissue. It carries a high recurrence rate and a significant potential for malignant transformation. Human papilloma virus (types 6 and 11) has been implicated as an etiologic agent for this tumor. Since this disease is rare and no controlled studies exist, radical excision of this anogenital lesion is generally recommended as the first line therapy and close vigilance and followup are essential.

 

 

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Figure 1: Buschke-Lowenstein tumor presenting as an extensive, erosive, exophytic and cauliflower-like growth involving the suprapubic, external genitalia and perianal region

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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Keywords

Buschke-L÷wenstein tumor
Human papilloma virus
Immunocompetent patient

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