Intoxication au plomb révélant une drépanocytose
Ahmed Mougui, Imane El Bouchti
The Pan African Medical Journal. 2018;30:305. doi:10.11604/pamj.2018.30.305.16222

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Intoxication au plomb révélant une drépanocytose

Cite this: The Pan African Medical Journal. 2018;30:305. doi:10.11604/pamj.2018.30.305.16222

Received: 31/05/2018 - Accepted: 10/08/2018 - Published: 31/08/2018

Mots clés: Drépanocytose, plomb, ostéonécrose aseptique

© Ahmed Mougui et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/30/305/full

Corresponding author: Ahmed Mougui, Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc (a.mougui88@gmail.com)


Intoxication au plomb révélant une drépanocytose

Lead intoxication revealing sickle cell disease

Ahmed Mougui1,&, Imane El Bouchti1

 

1Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc

 

 

&Auteur correspondant
Ahmed Mougui, Service de Rhumatologie, CHU Mohammed VI, BP 2360 principal, Avenue Ibn Sina, Marrakech, Maroc

 

 

English abstract

We here report the case of a 18 year old patient with two brothers who died from sickle cell anemia. He had a 5-day history of diffuse bone pain. He had drunk a preparation containing lead to obtain an analgesic effect without improvement. Radiographic examination showed a condensation due to the presence of lead in the digestive tract, associated with aseptic osteonecrosis of the two femoral heads on the X-ray of the pelvis (A) and of the vertebrae in H on the X-ray of the dorso-lumbar spine (B). These signs were suggestive of sickle cell anemia. The diagnosis was confirmed by hemoglobin electrophoresis test showing haemoglobin S at 79%.


Key words: Sickle cell disease, lead, aseptic osteonecrosis



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Patient de 18 ans, ayant deux frères décédés par drépanocytose. Présente depuis 5 jours des douleurs osseuses diffuses. Il avait bu une préparation contenant du plomb dans un but antalgique, sans amélioration. Le bilan radiographique montre, une condensation liée à la présence du plomb dans le tube digestif, avec une ostéonécrose aseptique des deux têtes fémorales sur la radiographie du bassin face (A), et des vertèbres en H sur la radiographie du rachis dorsolombaire profil (B). Ces signes sont évocateurs de la drépanocytose. Le diagnostic est confirmé par l'électrophorèse d'hémoglobine montrant une hémoglobine S à 79%.

Figure 1: A) radiographie du bassin face montrant la condensation digestive et l'ostéonécrose aseptique des têtes fémorales; B) radiographie du rachis dorsolombaire montrant des vertèbres en H

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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Keywords

Drépanocytose
Plomb
Ostéonécrose aseptique

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