Invasive hydatidiform mole in the cervix
Houssine Boufettal, Naïma Samouh
The Pan African Medical Journal. 2018;29:27. doi:10.11604/pamj.2018.29.27.10675

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Invasive hydatidiform mole in the cervix

Cite this: The Pan African Medical Journal. 2018;29:27. doi:10.11604/pamj.2018.29.27.10675

Received: 05/09/2016 - Accepted: 31/10/2016 - Published: 12/01/2018

Key words: Invasive mole, cervix, gestational trophoblastic tumor, chemotherapy

© Houssine Boufettal et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/29/27/full

Corresponding author: Houssine Boufettal, Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc (mohcineb@yahoo.fr)


Invasive hydatidiform mole in the cervix

Houssine Boufettal1,&, Naïma Samouh1

 

1Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc

 

 

&Corresponding author
Houssine Boufettal, Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Hassan II University of Casablanca, Casablanca, Maroc

 

 

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A patient aged 43-years, multiparous consulted for uterine bleeding of average abundance. The examination revealed a burgeoning lesion of the cervix, which came from the uterine endocervix, measuring two centimeters. The uterus was increased in size measuring 88 mm long and 67 mm in anteroposterior diameter. There were no adnexal mass. Pelvic ultrasound showed a heterogeneous snowflake mass measuring 29 mm in anteroposterior diameter. Beta-h-CG (human chorionic gonadotrophin) quantitative plasma were highly increased to 854212 IU / ml. Histological study of aspirate objectified a complete hydatidiform mole. The staging featuring a thoraco-abdominopelvic CT scan, chest radiography, ultrasound abdomen and pelvis was normal. Pathological examination of the hysterectomy piece objectified an invasive mole to cervical and uterine location. A methotrexate-based agent chemotherapy was introduced. The evolution was marked by the gradual decline of the mass until it disappearance within four months. Plasma beta-h-CG had regressed and were normalized after two months of treatment. The outcome was favorable. With a follow-up of 24 months, no recurrence was noted.

 

 

Figure 1: pathological examination of the hysterectomy piece objectified an invasive mole in cervical spine (arrow) and uterine

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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