Tuberous sclerosis: a case report
Ahmed Bouhamidi, Mohammed Boui
The Pan African Medical Journal. 2018;29:102. doi:10.11604/pamj.2018.29.102.14905

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Tuberous sclerosis: a case report

Cite this: The Pan African Medical Journal. 2018;29:102. doi:10.11604/pamj.2018.29.102.14905

Received: 18/01/2018 - Accepted: 26/01/2018 - Published: 07/02/2018

Key words: Tuberous sclerosis, Bourneville´s disease, angiofibromas

© Ahmed Bouhamidi et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/29/102/full

Corresponding author: Ahmed Bouhamidi, Military Hospital of Instruction Mohammed V, Department of Dermatology, Rabat, Morocco (docteurbouhamidi@gmail.com)


Tuberous sclerosis: a case report

Ahmed Bouhamidi1,&, Mohammed Boui1

 

1Military Hospital of Instruction Mohammed V, Department of Dermatology, Rabat, Morocco

 

 

&Corresponding author
Ahmed Bouhamidi, Military Hospital of Instruction Mohammed V, Department of Dermatology, Rabat, Morocco

 

 

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An 11-year-old girl, from a consanguineous family. With history of suspected akinetic seizures and normal intelligence. Physical examination revealed several small-scattered facial angiofibromas that were histologically determined by skin biopsy. Hypomelanotic macules, shagreen patches on her back. Periungual fibromas were not seen. CT brain showed multiple calcified sub ependymal nodules and cortical tubers. Cardiological consult and ECG were normal. Neurological consult shows: normal status of conscience, without meningeal signs of irritation, cranial nerves without deficit, and no ataxia. No hamartomas or retinal achromic patches was noticed by ophthalmologic evaluation. Radiography of the chest, truncal CT was without abnormality. So with the above clinical findings, a diagnosis of Tuberous sclerosis was made, and the patient is under regular monitoring. Tuberous Sclerosis, also known as Bourneville's disease, is an autosomal dominant syndrome with variable clinical expression. The dermatologist plays an essential role in the history of the disease, since skin manifestations represent the most prevalent clinical features, enabling early diagnosis and intervention in its natural course.

 

Figure 1: (A) several facial angiofibromas; (B) hypomelanotic macules and shagreen patches; (C,D) CT brain with multiple calcified sub-ependymal nodules and cortical tubers

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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ISSN: 1937-8688. © 2018 - Pan African Medical Journal. All rights reserved