Rubeosis iridis
Dionysios Pagoulatos, Constantine Georgakopoulos
The Pan African Medical Journal. 2017;28:279. doi:10.11604/pamj.2017.28.279.13717

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Rubeosis iridis

Cite this: The Pan African Medical Journal. 29/11/2017 ;28:279. doi:10.11604/pamj.29/11/2017 .28.279.13717

Received: 27/08/2017 - Accepted: 06/10/2017 - Published: 29/11/2017

Key words: Neovascularization, diabetic retinopathy, neovascular glaucoma

© Dionysios Pagoulatos et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Corresponding author: Dionysios Pagoulatos, Department of Ophthalmology, Hippokration Hospital, Athens, Greece (

Rubeosis iridis

Dionysios Pagoulatos1,&, Constantine Georgakopoulos1


1Department of Ophthalmology, Hippokration Hospital, Athens, Greece, 2Department of Ophthalmology, Medical School, University of Patras, Patras, Greece



&Corresponding author
Dionysios Pagoulatos, Department of Ophthalmology, Hippokration Hospital, Athens, Greece



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A 49 year-old man with medical history of diabetes type 2, who presented to the ophthalmology clinic for decreased vision. His most recent hemoglobin A1c was 11.4%. His intraocular pressures were 19 mmHg OD and 35 mmHg OS. Posterior segment exam showed severe proliferative diabetic retinopathy in both eyes. Neovascularization of the iris (NVI), also known as rubeosis iridis, is when, blood vessels develop on the anterior surface of the iris in response to retinal ischemia. This condition is often associated with diabetes in advanced proliferative diabetic retinopathy, central retinal vein occlusion, ocular ischemic syndrome and chronic retinal detachment. These new blood vessels may cover the trabecular meshwork and give rise to neovascular glaucoma. Patients with NVI are prone to spontaneous hyphemas as these blood vessels are fragile. Patients with proliferative diabetic retinopathy who develop NVI are treated with panretinal photocoagulation with or without an intravitreal injection of an anti-VEGF medication and with glaucoma treatment.


Figure 1: rubeosis iridis















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Figure 1: rubeosis iridis


Diabetic retinopathy
Neovascular glaucoma

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