Pseudotumoral form of granulomatosis with polyangiitis
Fadwa Mekouar, Naoual El Omri
The Pan African Medical Journal. 2017;26:173. doi:10.11604/pamj.2017.26.173.12195

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Pseudotumoral form of granulomatosis with polyangiitis

Cite this: The Pan African Medical Journal. 2017;26:173. doi:10.11604/pamj.2017.26.173.12195

Received: 07/03/2017 - Accepted: 10/03/2017 - Published: 27/03/2017

Key words: Cough, granulomatosis with polyangiitis, ANCA

© Fadwa Mekouar et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/26/173/full

Corresponding author: Naoual El Omri, Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco (elomrinaoual@gmail.com)


Pseudotumoral form of granulomatosis with polyangiitis

Fadwa Mekouar1,&, Naoual El Omri1

 

1Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco

 

 

&Corresponding author
Naoual El Omri, Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco

 

 

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A 65-year-old woman, non-smoker presented with a two-month history of cough. She also complained of arthralgia and weight loss. The clinical examination revealed a febrile patient. The chest radiograph and the scanner revealed right upper lobar mass, with spiculated contours (A, B). Biology showed an inflammatory syndrome. Polymerase chain reaction for Mycobacterium tuberculosis and tumor markers was negative. A lung biopsy showed non caseous granulomatous vasculitis. The cytoplasmic antineutrophil cytoplasmic antibody (cANCA/PR3/ANCA) showed a positive result; Wegener's granulomatosis was finally confirmed. The patient was treated with prednisone and cyclophosphamide with favorable outcome. A follow-up chest radiography two weeks after treatment showed resolving pulmonary lesions (C).

Figure 1: A) chest radiography revealed right upper lobar mass, with spiculated contour; B) chest scanner revealed right upper lobar mass, with spiculated contours; C) chest radiography two weeks after treatment showed resolving pulmonary lesions

 

 

 

 

 

 

 

 


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