Mediastinal and peripheral lymphadenopathy
Khaoula Elatiqi, Najiba Yassine
The Pan African Medical Journal. 2015;22:332. doi:10.11604/pamj.2015.22.332.7350

Create an account  |  Sign in
EPI Helina 2017
"Better health through knowledge sharing and information dissemination "

Images in medicine

Mediastinal and peripheral lymphadenopathy

Cite this: The Pan African Medical Journal. 2015;22:332. doi:10.11604/pamj.2015.22.332.7350

Received: 24/06/2015 - Accepted: 12/11/2015 - Published: 03/12/2015

Key words: Lymphadenopathy, lymphoma, tuberculosis

© Khaoula Elatiqi et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/22/332/full

Corresponding author: khaoula Elatiqi, Department of Respiratory diseases, Ibn roshd University Hospital, Casablanca, Morocco (khaoulaelatiqi@hotmail.com)


Mediastinal and peripheral lymphadenopathy

 

Khaoula Elatiqi1,&, Najiba Yassine1

 

1Department of Respiratory diseases, Ibn roshd University Hospital, Casablanca, Morocco

 

 

&Corresponding author
khaoula Elatiqi, Department of Respiratory diseases, Ibn roshd University Hospital, Casablanca, Morocco

 

 

Image in medicine

A 32-year-old man, with no history of cigarette smoking, had four weeks history of non productive cough, chest pain and myalgias. Physical examination revealed a painless bilateral cervical lymphadenopathy, the respiratory examination was normal. Chest radiography showed an enlarged upper and middle mediastinum (A). Computed tomography (CT) of the thorax showed a large and non homogeneous mass in the anterior and middle mediastinum and a small pericardial effusion, with displacement of vascular structures (B). Laboratory analysis revealed an elevated lactate dehydrogenase level of 690 IU per liter. The exicional biopsy of the left cervical lymph node revealed a caseating and necrotizing granulomatous lesions and confirmed a diagnosis of lymph node tuberculosis. The biopsy of the right cervical lymph node established a B-cell non-Hodgkin lymphoma, and so a rare association with tuberculosis. The patient received anti-tuberculosis therapy. The regimen was based on two months of ethambutol, rifampicin, pyrazinamide and isoniazid, followed by four months of rifampicin and isoniazid. He received also chemotherapy with cyclophosphamide, adriamycin, vincristine and prednisolone. The patient presented, two months later with clinical and radiographic improvement.

 

 

Figure 1: (A) a chest radiography showing an enlarged mediastinum; (B) a thoracic CT showing a large and inhomogeneous mass in the mediastinum

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


The Pan African Medical Journal articles are archived on Pubmed Central. Access PAMJ archives on PMC here

Volume 27 (May - August 2017)

Article tools

This article authors

On Pubmed
On Google Scholar

Navigate this article

Rate this article

Altmetric

PAMJ is a member of the Committee on Publication Ethics

PAMJ is published in collaboration with the African Field Epidemiology Network (AFENET)
Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, Ulrichsweb, More to come . Member of COPE.

ISSN: 1937-8688. © 2017 - Pan African Medical Journal. All rights reserved