References

  1. Ruocco E, Ruocco V, Tornesello ML, Gambardella A, Wolf R, Buonaguro FM. Kaposi's sarcoma: etiology and pathogenesis, inducing factors, causal associations and treatments: facts and controversies. Clinics in dermatology. 2013 Jul 1; 31(4): 413-22. PubMed | Google Scholar

  2. Pfeiffer RM, Wheeler WA, Mbisa G, Whitby D, Goedert JJ, Mbulaiteye SM. Geographic heterogeneity of prevalence of the human herpesvirus 8 in sub-Saharan Africa: clues about etiology. Ann Epidemiol. 2010 Dec; 20(12): 958-63. PubMed | Google Scholar

  3. Hengge UR, Ruzicka T, Tyring SK, Stuschke M, Roggendorf M, Schwartz RA, Seeber S. Update on Kaposi's sarcoma and other HHV8 associated diseases; Part 1: epidemiology, environmental predispositions, clinical manifestations and therapy. The Lancet infectious diseases. 2002; 2(5): 281-292. PubMed | Google Scholar

  4. Russo JJ, Bohenzky RA, Chien MC, Chen J, Yan M, Maddalena D, Moore PS. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proceedings of the National Academy of Sciences. 1996; 93(25): 14862-14867. PubMed | Google Scholar

  5. Samols MA, Hu J, Skalsky RL, Renne R. "Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus". Journal of Virology. 2005; 79(14): 9301-5. PubMed | Google Scholar

  6. Samaniego F, Pati S, Karp JE, Prakash O, Bose D. Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation. J Natl Cancer Inst Monogr. 2001; (28): 15-23. PubMed | Google Scholar

  7. Choi JK, Lee BS, Shim SN, Li M, Jung JU. Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome. Journal of virology. 2000; 74(1): 436-446. PubMed | Google Scholar

  8. Cho NH, Choi YK, Choi JK. Multi-transmembrane protein K15 of Kaposi's sarcoma-associated herpesvirus targets Lyn kinase in the membrane raft and induces NFAT/AP1 activities. Experimental & molecular medicine. 2008 Oct; 40(5): 565. PubMed | Google Scholar

  9. Martin JN. Diagnosis and epidemiology of human herpesvirus 8 infection. Semin Hematol. 2003 Apr; 40(2): 133-42. PubMed | Google Scholar

  10. Ziegler JL, Newton R, Katongole-Mbidde E, Mbulataiye S, De Cock K, Wabinga H, Mugerwa J, Katabira E, Jaffe H, Parkin DM, Reeves G. Risk factors for Kaposi's sarcoma in HIV-positive subjects in Uganda. Aids. 1997 Nov 11; 11(13): 1619-26. PubMed | Google Scholar

  11. GnannJr JW, Pellett PE, Jaffe HW. Human herpesvirus 8 and Kaposi's sarcoma in persons infected with human immunodeficiency virus. Clinical Infectious Diseases. 2000 Apr1; 30(1): S72-6. Google Scholar

  12. Laney AS, Cannon MJ, Jaffe HW, Offermann MK, Ou CY, Radford KW, Patel MM, Spira TJ, Gunthel CJ, Pellett PE, Dollard SC. Human herpesvirus 8 presence and viral load are associated with the progression of AIDS-associated Kaposi's sarcoma. Aids. 2007 Jul 31; 21(12): 1541-5. PubMed | Google Scholar

  13. Tumwine LK, Orem J, Kerchan P, Byarugaba W, Pileri SA. EBV, HHV8 and HIV in B cell non Hodgkin lymphoma in Kampala, Uganda. Infectious agents and cancer. 2010; 5: 12. PubMed | Google Scholar

  14. Stürzl M, Brandstetter H, Roth WK. Kaposi's sarcoma: a review of gene expression and ultrastructure of KS spindle cells in vivo. AIDS research and human retroviruses. 1992; 8(10): 1753-1763. Google Scholar

  15. Machado PRL, Farias KJS, Pereira MGM, Freitas PPDSD, Fonseca BALD. Human herpesvirus 8 (HHV-8) detected by nested polymerase chain reaction (PCR) in HIV patients with or without Kaposi's sarcoma: an analytic cross-sectional study. Sao Paulo Medical Journal. 2016; 134(3): 187-192. PubMed | Google Scholar

  16. Cochran WG. Sampling techniques. John Wiley & Sons. 2007; 21.

  17. Kimanga DO, Ogola S, Umuro M. Prevalence and incidence of HIV infection, trends, and risk factors among persons aged 15?64 years in Kenya: results from a nationally representative study. Journal of acquired immune deficiency syndromes (1999). 2014 May 1; 66 Suppl 1: S13-26. PubMed | Google Scholar

  18. Onyango JF, Njiru A. Kaposis sarcoma in a Nairobi hospital. East African medical journal. 2004; 81(3): 120-3. PubMed | Google Scholar

  19. Duprez R, Hbid O, Afonso P, Quach H, Belloul L, Fajali N, Ismaili N, Benomar H, Tahri EH, Huerre M, Quintana-Murci L. Molecular epidemiology of the HHV-8 K1 gene from Moroccan patients with Kaposi's sarcoma. Virology. 2006 Sep 15; 353(1): 121-32. PubMed | Google Scholar

  20. Kasolo FC, Monze M, Obel N, Anderson RA, French C, Gompels UA. Sequence analyses of human herpesvirus-8 strains from both African human immunodeficiency virus-negative and-positive childhood endemic Kaposi's sarcoma show a close relationship with strains identified in febrile children and high variation in the K1 glycoprotein. Journal of General Virology. 1998 Dec 1; 79(12): 3055-65. PubMed | Google Scholar

  21. Kakoola DN, Sheldon J, Byabazaire N, Bowden RJ, Katongole-Mbidde E, Schulz TF, Davison AJ. Recombination in human herpesvirus-8 strains from Uganda and evolution of the K15 gene. Journal of General Virology. 2001 Oct 1; 82(10): 2393-404. PubMed | Google Scholar

  22. White T, Hagen M, Gudza I, White IE, Ndemera B, Gwanzura L, Borok M, Campbell TB. Genetic diversity of the Kaposi's sarcoma herpesvirus K1 protein in AIDS-KS in Zimbabwe. Journal of Clinical Virology. 2008 Jun 1; 42(2): 165-71. PubMed | Google Scholar

  23. Choussy O, Haverbeke CV, Babin E, Francois A, Duval-Modeste AB, Dehesdin D. Unusual presentation of oropharyngeal Kaposi's sarcoma. Head & Neck: Journal for the Sciences and Specialties of the Head and Neck. 2008 Mar; 30(3): 411-5. PubMed | Google Scholar

  24. Crum-Cianflone NF, Hullsiek KH, Ganesan A, Weintrob A, Okulicz JF, Agan BK, Infectious Disease Clinical Research Program HIV Working Group. Is Kaposi's Sarcoma Occurring at Higher CD4 Counts Over the Course of the HIV Epidemic. AIDS (London, England). 2010 Nov 27; 24(18): 2881. PubMed | Google Scholar

  25. Maurer T, Ponte M, Leslie K. HIV-associated Kaposi's sarcoma with a high CD4 count and a low viral load. New England Journal of Medicine. 2007 Sep 27; 357(13): 1352-3. PubMed | Google Scholar

  26. Leidner RS, Aboulafia DM. Recrudescent Kaposi's sarcoma after initiation of HAART: a manifestation of immune reconstitution syndrome. AIDS Patient Care & STDs. 2005 Oct 1; 19(10): 635-44. PubMed | Google Scholar

  27. Martin DF, Kuppermann BD, Wolitz RA, Palestine AG, Li H, Robinson CA, Roche Ganciclovir Study Group. Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. New England Journal of Medicine. 1999 Apr 8; 340(14): 1063-70. PubMed | Google Scholar

  28. Yarchoan R, Tosato G, Little RF. Therapy insight: AIDS-related malignancies-the influence of antiviral therapy on pathogenesis and management. Nature Reviews Clinical Oncology. 2005 Aug; 2(8): 406. PubMed | Google Scholar

  29. Tornesello ML, Biryahwaho B, Downing R, Hatzakis A, Alessi E, Cusini M, Ruocco V, Katongole-Mbidde E, Loquercio G, Buonaguro L, Buonaguro FM. Human herpesvirus type 8 variants circulating in Europe, Africa and North America in classic, endemic and epidemic Kaposi's sarcoma lesions during pre-AIDS and AIDS era. Virology. 2010 Mar 15; 398(2): 280-9. PubMed | Google Scholar

  30. Mohanna S, Maco V, Bravo F, Gotuzzo E. Epidemiology and clinical characteristics of classic Kaposi's sarcoma, seroprevalence, and variants of human herpesvirus 8 in South America: a critical review of an old disease. International journal of infectious diseases. 2005 Sep 1; 9(5): 239-50. PubMed | Google Scholar

  31. Mwakigonja AR, Pyakurel P, Kokhaei P, Pak F, Lema LK, Kaaya EE, Biberfeld P. Human herpesvirus-8 (HHV-8) sero-detection and HIV association in Kaposi's sarcoma (KS), non-KS tumors and non-neoplastic conditions. Infectious agents and cancer. 2008 Dec; 3: 10. PubMed | Google Scholar

  32. Tembo R, Kaile T, Kafita D, Chisanga C, Kalonda A, Zulu E, Samutela M, Polepole P, Kwenda G. Detection of Human Herpes Virus 8 in Kaposi's sarcoma tissues at the University Teaching Hospital, Lusaka, Zambia. Pan Afr Med J. 2017 Jun 22; 27: 137. PubMed | Google Scholar

  33. Phipps W, Ssewankambo F, Nguyen H, Saracino M, Wald A, Corey L, Orem J, Kambugu A, Casper C. Gender differences in clinical presentation and outcomes of epidemic Kaposi sarcoma in Uganda. PloS one. 2010 Nov 12; 5(11): e13936. PubMed | Google Scholar

  34. vanBogaert LJ. Clinicopathological proficiency in the diagnosis of Kaposi's sarcoma. ISRN AIDS. 2012 May 30; 2012: 565463. PubMed | Google Scholar