Introduction: psychopharmacology today faces serious challenges, especially related inappropriate drug choices, abuse and resulting side effects. The aim of this pharmacy based study in the City of Tiflet was to profile the prescription and usage patterns of psychotropic drugs.

Methods: this study was conducted in the pharmacies of the City of Tiflet (Morocco). Descriptive statistics of 5125 prescriptions collected from 21 pharmacies were analysed, and summarized as means, percentages and proportions where appropriate.

Results: the patterns of psychotropic drugs use were similar, compared to Western Countries, especially for anxiolytics/hypnotics, neuroleptics and anti-depressants. A poor monitoring of the treatment, and the lack of control of its side effects were major concerns. General practitioners ranked first among doctors who prescribed psychotropic drugs (48.5%), followed by psychiatrists (41.7%), and the rest of the prescriptions come from other specialists (neurologists, cardiologists, gynaecologists...). Among psychotropic drugs, anxiolytics dominated prescriptions (52.0%), followed by neuroleptics (29.0%) and anti-depressants (19.0%). Men consumed more psychotropic drugs than women (51.8% against 48.2% respectively).

Conclusion: anxiolytics/hypnotics constitute the main class of psychotropic drugs prescribed in the Tiflet City, followed by neuroleptics and anti-depressants. Nearly half of the population currently receive prescribed psychotropic drugs from general practitioners. Psychiatrists are less involved in the prescription and monitoring of these patients. This could predispose the population to addiction, drug misuse, intoxication, and at times, misdiagnosis of serious psychiatric illnesses. Our study highlights the urgency of reinforcing psychotropic prescription regulation and monitoring in Tiflet city.